Prevalent Medications For Treating Alzheimer’s Disease

Alzheimer's disease pic

Alzheimer’s disease
Image: webmd.com

Serving pharmaceutical patients throughout the Roanoke, Virginia, area, Ashok Pinnamaraju has a strong knowledge of the needs of senior patients, and regularly visits nursing homes. Though his work with seniors, Ashok Pinnamaraju has experience with drugs that address the cognitive symptoms associated with Alzheimer’s disease.

There are two basic types of FDA-approved medications designed to mitigate confusion and memory loss: cholinesterase inhibitors, and memantine. The latter regulates activities of the chemical glutamate, which is critical in information processing, and enables some people to think more clearly and better perform daily activities. Common side effects include dizziness, constipation, and headache.

By contrast, cholinesterase inhibitors work to prevent the memory and learning-related chemical messenger acetylcholine from breaking down. This promotes high levels of acetylcholine, associated with proper nerve cell communication. Typically tolerated well by the body, cholinesterase inhibitors occasionally have side effects such as appetite loss, nausea, and an increase in bowel movement frequency.

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The Effects of NSAID Drugs

 

NSAID pic

NSAID
Image: webmd.com

A respected presence in the Roanoke, Virginia, community, Ashok Pinnamaraju owns the Williamson Road Pharmacy, providing client-centered service at his location as well as in local nursing homes. Ashok Pinnamaraju has an extensive knowledge of nonsteroidal anti-inflammatory drugs (NSAID), which are among the most common prescriptions for addressing arthritis.

Common non-prescription NSAIDs include ibuprofen and aspirin. More than simply pain relievers, they help reduce fevers and inflammation. Aspirin is also an anti-coagulant and can be effective in addressing heart disease through reduction of clotting. Unfortunately, the drug can increase susceptibility to bruising and decrease kidney function, while increasing the prevalence of ulcers and nausea.

With various formulas and strengths available, NSAIDs work to prevent the enzyme cyclooxygenase (COX) from fulfilling its core functions. They are effective against COX-2, which is generated when joints are inflamed or injured, and COX-1, which helps prevent harsh digestive chemicals and acids from eating away the stomach lining.

For those addressing inflammation, COX-2 inhibitors such as Celebrex are recommended, as they avoid the upset stomach and bleeding associated with traditional NSAIDs. However, these drugs are not effective against heart disease, and should not be taken in tandem with aspirin and other traditional NSAIDs.