The Effects of NSAID Drugs




A respected presence in the Roanoke, Virginia, community, Ashok Pinnamaraju owns the Williamson Road Pharmacy, providing client-centered service at his location as well as in local nursing homes. Ashok Pinnamaraju has an extensive knowledge of nonsteroidal anti-inflammatory drugs (NSAID), which are among the most common prescriptions for addressing arthritis.

Common non-prescription NSAIDs include ibuprofen and aspirin. More than simply pain relievers, they help reduce fevers and inflammation. Aspirin is also an anti-coagulant and can be effective in addressing heart disease through reduction of clotting. Unfortunately, the drug can increase susceptibility to bruising and decrease kidney function, while increasing the prevalence of ulcers and nausea.

With various formulas and strengths available, NSAIDs work to prevent the enzyme cyclooxygenase (COX) from fulfilling its core functions. They are effective against COX-2, which is generated when joints are inflamed or injured, and COX-1, which helps prevent harsh digestive chemicals and acids from eating away the stomach lining.

For those addressing inflammation, COX-2 inhibitors such as Celebrex are recommended, as they avoid the upset stomach and bleeding associated with traditional NSAIDs. However, these drugs are not effective against heart disease, and should not be taken in tandem with aspirin and other traditional NSAIDs.